Sentence examples for by its induction of from inspiring English sources

The released factor retained activity, as shown by its induction of ERK1/2 activation and affording cytoprotection in rat neonatal cardiomyocyte cultures.

Preliminary mechanistic studies indicated that the antiproliferative efficacy of 15k was mediated by its induction of apoptosis, loss of mitochondrial membrane potential and cell cycle arrest at the sub-G1 phase.

There is some evidence supporting the concept that bFGF facilitates binding of VEGF121 by its induction of VEGFR2 expression [ 32].

Prior studies have proposed that the growth inhibition function of AR signalling in normal prostatic luminal cells is mediated by its induction of CDKN1B expression [ 30].

Thus, D. japonica extract has been shown to have beneficial effects and is a potent source of neuroprotective agents, as evidenced by its induction of neurotrophic factors.

Another study suggested that the anti-osteoclastic effect of tacrolimus might be explained by its induction of apoptosis in osteoclasts [ 23].

Therefore, we next examined the involvement of GSK-3 β by Nur77 in its induction of β-catenin.

Reversal, by DMSO, of the effects of SAD on MEPM cell growth, on PCNA expression and on all components of the PKA, but not of PKC, pathway suggests that the perturbation of the PKA pathway by SAD is relevant to its induction of CP in mice.

Activation of NF-κB was confirmed by inductions of its messenger and further by induction of its target proinflammatory cytokines RANTES (Ccl5), Tnf and Il1b.

The role of H2O2 as a promoter of neoplastic transformation is supported by the modulation of the PI3K/AKT signaling pathway due to oxidation of the PTP1B [ 123, 124] and of PTEN [ 125] and supported by the inhibition of its induction in the presence of anti-oxidant scavengers [ 126].

Kogawa, M. et al. Sclerostin regulates release of bone mineral by osteocytes by induction of carbonic anhydrase 2. J Bone Miner Res 28, 2436 2448 (2013).