Sentence examples for by its increased expression from inspiring English sources

The increased expression and activity of Syk in SLE T cells is evidenced by its increased expression in the lipid rafts and increased association with downstream molecules involved in actin polymerization and calcium signaling, namely Vav-1 and PLCγ1 [ 24].

This caspase activation would probably have resulted from increased levels of other proapototic mediators like Bax, as evidenced by its increased expression after treatment with TD.

This gene is regulated by p53 and its increased expression in response to BaP has been shown previously [ 3].

Tumor sections were stained for progesterone receptor (PGR), as PGR expression is mediated by ER signaling and its increased expression correlates with ER activation.

Given its modulation by P4 in vivo and its increased expression in pregnant heifers likely due to IFNT [ 63], as well as detection of PLIN2 family members in ULF of cattle, it is likely that PLIN2 contributes to the secretion and /or transport of TAG into the ULF as an energy source for the developing conceptus during elongation.

In addition, high expression of MIC1 in ESCC tissues was observed by TMA and RT-PCR, and its increased expression in our serum and tissue samples were significantly correlated with a higher N stage of ESCC, implying that MIC1 overexpression might play a role in tumor progression of ESCC, especially in lymph node metastasis.

p53 is inactivated in approximately half of human cancers, either by mutations, or by increased expression of its inhibitors, which enhances tumour survival and development.

We found that leaf miR5266 was induced by B-deficiency accompanied by increased expression of its target gene: ammonium transporter 1 1 (Table  2), which disagrees with our report that the abundance of miR5266 was lower in B-deficient citrus roots than in controls, while the expression level of ammonium transporter 1 1 was higher in the former [ 8].

We also observed that the increased transcription of BCAM0931 was accompanied by the increased expression of its flanking gene ankB (BCAM0930; Table 3).

Moreover, protein expression and functional activation of Bax should not be necessarily mirrored by an increased expression of its mRNA.

The overexpression of the receptor may also be accompanied by an increased expression of its activating ligands [ 22], which suggests the existence of a positive feedback loop that reinforces the aberrant signaling.