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Moreover, derivatization influences the ionization efficacies by introducing additional charges.
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Dimerisation of such photosensitizers in solution in a broad concentration range can be suppressed by introducing additional positive charges in the side chains.
Additional gains in performance can be achieved by introducing additional redundancy through coding.
It is concluded that the performance limits must be refined by introducing additional parameters.
We propose an alternative compensation of this asymmetry by introducing additional sources of electric field.
This is achieved by introducing additional constraints, and by slightly tightening the original constraints.
In F0, K7 and R33 introduce additional positive charges that are also observed in some Ras/Rap1-binding domains (Kiel et al, 2005) (Supplementary Figure 2).
Such direct viewing avoids introducing additional transformations required by mirror-viewing [23], [60], [61].
Such direct viewing avoids introducing additional transformations required by mirror-viewing [14], [25].
Since phosphorylation at these positions would introduce additional negative charge near the phosphate backbone, these PTMs could significantly enhance unwrapping; however, this remains to be directly tested.
One potential explanation for not observing an effect on channel properties by introducing an additional negative charge for S193E would be that residue S193 is not exposed to the VDAC pore lumen.
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