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This indicates that the interaction of organic molecules with pyrite surfaces under anoxic conditions is dictated by interactions with specific surface sites (thiol or iron surface sites) rather than electrostatic forces.
The results of this study suggest that the interaction of a wide range of low-molecular weight organic compounds is dictated by interactions with specific surface sites and not by overall electrostatic forces.
TACC proteins were then recruited to complexes involved in protein translation, RNA processing and transcription by interactions with specific bridging proteins.
These conclusions further support the emerging model in which the ubiquitylating capacity of E2s is dictated both by specific residues within the enzyme and by interactions with specific E3 ligase partners (e.g., refs (10) and (38)).
Rop GTPases are activated mostly by a type of GEF proteins absent in Opisthokonts – the PRONE-GEFs [ 105] - whose activity is regulated by interactions with specific transmembrane Ser/Thr receptor kinases (RLKs; [ 105, 106]).
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Nucleotides such as ATP can act as extracellular effector molecules by interaction with specific cellular receptors known as P2-purinoceptors.
By interaction with specific receptors, hyaluronan is capable of intracellular signal transduction that can promote the malignant phenotype [ 14].
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors.
Another mechanism may be through sequence-specific motifs that direct miRNA trafficking by interaction with specific chaperone proteins (Bolukbasi et al., 2012; Villarroya-Beltri et al., 2013).
LPA's activity is mediated by interaction with specific G protein-coupled receptors, six of which have been definitively identified (LPA1-6) [ 7, 11, 12].
It has been suggested that these effects are mediated by interaction with specific opioid and somatostatin receptors although further studies confirming this mode of action are needed.
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