Sentence examples for by interactions with alternative from inspiring English sources
Functional specialization of BORIS isoforms could be generated by interactions with alternative partner proteins, and by novel DNA binding activities of isoproteins that do not correspond to CTCF-recognized sites.
Nucleotide-binding specificity is determined not only by possible contacts with nucleotides but also by steric exclusion of interactions with alternative nucleotides (reviewed in [ 25]).
Escape mutations in HIV-1 cytotoxic T cell (CTL) epitopes can abrogate recognition by the TCR of HIV-1-specific CD8+ T cells, but may also change interactions with alternative MHC class I receptors.
However, blockade of ILT4 by antibodies did not fully abrogate binding of the respective tetramers/pentamers to monocytes, suggesting that interactions with alternative MHC class I receptors on myelomonocytic cells might contribute to the recognition of these tetramers/pentamers.
What unites these approaches is the insight that human intelligence develops through interactions with objects in the environment and is shaped profoundly by interactions with other human beings.
We can enhance binding specificity of a protein by computationally optimizing its sequence for better interactions with one target and worse interaction with alternative target(s).
Modularity in the components of a signaling pathway permits a large flexibility by interaction with proteins that can play a regulatory role of its activity, or alter the balance between alternative signal response pathways.
Four different mature mRNAs of MIK are generated by alternative splicing, and the resulting polypeptides display different kinase activity and are differentially activated by interaction with the MARK receptor [ 50].
However, it is recognized that enzyme performance is reduced during lignocellulose hydrolysis by interaction with lignin or lignin carbohydrate complex (LCC), so the selection or engineering of enzymes with reduced lignin interaction offers an alternative means of enzyme improvement.
