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hnRP1 enhances translation of p27 mRNA by interacting with its 5'-untranslated region, and the interaction of UCA1 with hnRNP1 suppresses the p27 protein level by competitive inhibition.
As acetylation regulates the activity of both histones and nonhistone proteins (Lane & Chabner, 2009; Spange et al, 2009), it is tempting to speculate that by interacting with its cellular (de)acetylators the virus may modulate acetylation signalling in the host cells and modify the cellular environment to successfully accomplish its life cycle.
Evolvable Hardware (EHW) is hardware that can dynamically change its behavior and architecture by interacting with its environment.
However, a truly autonomous robot should develop perceptive abilities on its own, by interacting with its environment, and adapting to new situations.
By interacting with its preferred ligand ephrin-B2, which is also a transmembrane protein, EphB4 plays a role in a variety of physiological and pathological processes ranging from bone remodeling to cancer malignancy.
Docking analysis suggests that the synthesized compounds were anchored well in the catalytic site and extending to the entrance of binding pocket and thus restrict the mobility of the flap by interacting with its key amino acid residues.
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Therefore, the results suggest that p53 induces miR-509-5p miR-509-5p miR-509-5py intexpressionith its promoter.
The primary function of mdm2 is inhibition of p53 activity by directly interacting with its specific DNA binding/transactivation sites (Ashcroft and Vousden, 1999).
Because Yrt is a FERM protein that negatively regulates Crb by directly interacting with its FBM (Laprise et al., 2006), Yrt appeared as a likely candidate in mediating the foscrb Y10A mutant phenotype.
PALB2 creates the BPB complex by interacting with BRCA1 via its own N-terminal coiled-coil domain and with BRCA2 via its own C-terminal WD40 domain [41].
Whether he's playing a game or not, Sam Bird has made a quick impression on the villa by interacting with some of its biggest characters immediately.
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by colliding with its
by negotiating with its
by rinsing with its
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by feeding with its
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