The Release4 predictions were produced using GLEAN [9], an algorithm that creates consensus gene predictions by integrating available experimental data such as expressed sequence tags (ESTs) and proteomics data.
We have shown that a mathematical model may contribute substantially to both aspects by integrating available empirical data into a concerted whole, by identifying which processes are most sensitive to variation in parameter values and by identifying those that are not likely to be under strict regulatory control.
Thus, an important step towards a dynamic understanding of the functions and behaviors relevant to a particular system is modeling protein interactions, by integrating available knowledge on signaling pathways with novel high-throughput protein expression data.
By integrating the available data into a mathematical model that accurately represents the current understanding and comparing computational predictions to observations we sought to (a) identify inconsistencies in present knowledge, (b) propose resolutions, and (c) examine their functional implications.
Thus, by integrating currently available data of TF and protein binding, we find evidence for the existence of in-hubs in the regulatory network of yeast.
TCl-Db, a Taxonomy and Classification Database, was developed to increase the accessibility and transparency of taxonomic data by integrating data from the available data sources.
Li et al. [27] identified 20,163 putative lncRNAs in maize by integrating the available EST data, annotated information of maize genome, and RNA-seq datasets obtained from 30 different experiments.
To address the objective, an induced economic impact assessment model was developed by integrating quantitative publically available data sources with community-level qualitative data sources incorporating them into an input-output approach.
We have shown that ChIP-PED can improve the analysis of ChIPx data by integrating publicly available gene expression data.
Besides, it offers a customisable user-driven prioritisation integrating the available data as specified by the researcher.
