Sentence examples for by insufficient expression of from inspiring English sources
The knock-out of megalin expression in the kidneys of these megalinlox/lox; apoECre mice occurs in a mosaic pattern, with a considerable percentage of tubular cells expressing normal levels of megalin, presumably caused by insufficient expression of Cre recombinase.
Expression of the maize LC (MYC-type) and C1 (MYB-type) genes in the fruit of transgenic tomatoes resulted in a strong accumulation of kaempferol glucoside, but not in the accumulation of anthocyanins, a finding that was explained by insufficient expression of the gene encoding flavanone-3',5'-hydroxylase [ 55].
Based on the location of ccdc88c (Daple gene) at a site on the long arm of Chr 14, which is known to be frequently deleted in a variety of cancers (Suzuki et al., 1989; Hu et al., 2002; Rouault et al., 2012), we conclude that tumors harboring a focal deletion at that site are in part driven by insufficient expression of the tumor suppressor Daple.
Delayed wound healing could be accounted for by the insufficient expression of several regulatory proteins.
Patients were assigned to the control group for: (i) low availability of monoclonal antibodies, (ii) insufficient expression of tenascin by the tumour, or (iii) a history of allergic reactions; otherwise they would have been assigned to the treatment group and given RIT.
This would suggest that the incomplete rescue of two of the GE24185 phenotypes (loss of A5 pigmentation and held out wings) by the hsp83 dCTCF + transgene is likely due, at least in part, to the insufficient expression of dCTCF.
This led us to suspect that many of the unrecoverable mutants might have resulted from insufficient expression of the promoterless aphA-3 gene.
(vi) Finally, insufficient expression of the selection marker, as occurred with our promoterless Kmr gene, may result in false-positive identification of essential genes.
However, these studies overlooked the problem that the spinosyn biosynthetic pathway was unbalanced: the expression of six genes in the spinosyn biosynthetic pathway was insufficient; Saccharopolyspora spinosa accumulated useless compounds because of insufficient expression of SpnK.
The failure of rescue is unlikely to be due to insufficient expression because expression of the rescue construct significantly activated isthmus peristalsis, the other feeding motion in C. elegans, which is controlled by M4 (Song and Avery, 2012).
