Sentence examples for by inserting the mutation from inspiring English sources

This time the pattern was similar to that seen for receptors expressed in mammalian cells, as the greater increase in ACh sensitivity was seen for α3LTβ4 receptors, with a leftward shift of 47-fold (bottom of Table 2), significantly greater than the 10-fold shift produced by inserting the mutation in the β subunit (cf. the confidence intervals shown in Table 2).

He and his colleagues are also attempting to make an animal model of stuttering by inserting the human mutation into mice.

The PIPE method was also used to create two mutants by inserting the following point mutations in the SitA23 306 expression construct: H64A and E203A+D278A.

To confirm the effect of the ΔmelC mutation, a complementation test was performed by inserting the melC operon into the chromosome of YU5.

The researchers demonstrated their technique by inserting the DNA-binding machinto into human white blood cells that had mutations that cause severe combined immune deficiency.

They disrupted the function of DJ-1β by inserting a mutation into the middle of the gene.

By inserting point mutation into the Sec7 domain of tobacco ARF-GEF NtGNL1a, we have induced its BFA-sensitivity and thus uncovered its preferential role in the endocytosis of FM 4 64 and PIN1.

By inserting homologous mutations in the AChE and BChE cDNAs, they found that the mutation also resulted in endoplasmic reticulum retention of the two cholinesterases.

pcDNA3-HA-UCH L1 C90S and H161D mutants were generated by inserting a specific mutation at the Cys 90 and H161 sites in wild-type pcDNA3-HA-UCH L1 plasmid with the use of the Quik-Change Site Directed Mutagenesis Kit following the manufacturer's instructions (Stratagene).

These approaches not only generate insight into complex phenotypes, but the obtained knowledge can also be used to directly modify strains by inserting only the causative mutation(s).

To exclude, the changes that were possibly caused by inserting a splice mutation and/or 'humanization' of exon 47 (6), we additionally compared the expression profiles of the 6-week-old MPI11Q/11Q KI mice (n = 3) with their WT littermates (n = 3).