Sentence examples for by injection of mutant from inspiring English sources
Vps35 mutant mice were generated by injection of mutant embryonic stem (ES) cells obtained from Bay Genomics as described previously (Wen et al., 2011).
This defect is carried by the female gamete and can be rescued by direct injection of mutant ookinetes into the mosquito hemocoel, where oocysts develop.
Mouse chimeras were generated by C57BL/6 host blastocyst injection of mutant embryonic stem cell clones, and the chimeras obtained were bred with C57BL/6 mice to generate heterozygous Cthrc1 mice.
We first defined the time course of loss in spontaneous OR memory in both a transgenic mouse model of familial tauopathy, and a focal tauopathy model induced by injection of AAV containing a mutant tau cDNA.
Furthermore, we show that severe developmental defects in zebrafish embryos caused by morpholino injections targeting Pak are partially rescued by co-injection of wild-type human Pak1, but not by co-injection of mutant Pak1 mRNA disrupting either the LC8 binding or the NLS site.
However, these axon defects in pnpla6 morphants could not be rescued by co-injection of mutant mRNA (Fig. 3F,J).
Mutant N-Ras was expressed in zebrafish embryos at the one-cell stage by injection of synthetic RNA encoding wild-type or mutant N-Ras.
The recruitment of cells in response to mtCXCL12 was not significantly greater than that produced by injection of PBS (P>0.05); the failure of the mutant sequence to recruit leukocytes in vivo was apparent for all the leukocyte populations enumerated after differential staining.
The hypertriglyceridemia in apoc2 mutants is rescued by injection of plasma from wild-type zebrafish or by injection of a human APOC2 mimetic peptide.
These defects were partially rescued by injection of a preprocessed miR-430 family to the mutant (Giraldez et al. 2005).
They show that the hypertriglyceridemia in apoc2 mutants can be rescued by injection of plasma from wild-type zebrafish with functional Apoc2 or by injection of a human APOC2 mimetic peptide.
