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Using Capan-2 (wt-p53) model, we investigated the gene expression that was followed by Ingenuity network analysis (IPA) for pathway interactions.

The significance of each network, function, and pathway was determined by the scoring system provided by Ingenuity.

Amino acid metabolism was also the top function listed by Ingenuity pathway analysis for PCa bone metastases (Table S4).

Figure 6 shows the top two scoring gene networks obtained by Ingenuity Pathway analysis of this DOC-correlated gene set.

When required, the resulting lists of genes were subjected to analysis by Ingenuity Pathway Analysis (IPA, version 7.5, http://www.ingenuity.com/).com/

In this manner, TWIST1 and VAV3 are putative oncogenes involved in growth hormone signaling, as revealed by Ingenuity Pathway Analysis (Fig. 3C).

PPARα was identified as a significant hub in a high-ranking network generated by Ingenuity Pathways Analysis and confirmed by other investigators as significantly increased [60].

By Ingenuity Pathway Analysis (IPA), 14 canonical pathways represent the genes changed when orthochromatic cells are co-cultured with P. falciparum (Table 1, Supplementary Figure S1).

The functional analysis of pathways enriched in genes which changed expression after 6 or 24 hr treatment with Baf were generated by Ingenuity Pathways Analysis (Ingenuity® Systems, www.ingenuity.com).com

For pathway analysis of the microarray data, gene lists were analyzed by Ingenuity Pathway Analysis (IPA; Ingenuity® Systems, Redwood City, CA, http://www.ingenuity.com), a web-based bioinformatics tool.