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The models are built by inferring the structure of a protein (the target) from the structure of another putatively homologous protein solved by experimental methods (the template).
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However, here we only resurrect MVP in silico, with a combination of two protocols, first by reconstructing the ancestral sequence for each group (using PAML4 and FastML), and second by inferring the structures using I-TASSER.
In addition, raw SV data could be corrected by inferring the global structure of chromosomes because an optimal global structure would ignore false positive detection of aberrant adjacencies or correct wrongly estimated copy numbers.
It is inferred the structure suffers severe damage.
STRUCTURE can infer the population structure by using a variety of models, including the linkage model (17 ), which incorporates linkage disequilibrium due to correlations in ancestry between loci that reflects admixture between populations.
In this study, Wise2 compared the target protein (preference was given to pig protein sequences, followed by human, cattle and other mammals) to the pig genomic DNA sequence identified by BLAST to infer the gene structure based on a model that includes introns and frameshift errors.
Last, some important contributions in the field of complex systems have investigated some properties of groups that can be inferred by the structure of social links via clustering or community detection algorithms.
Log-likelihood and Δ K values showing the likely number of ancestral populations inferred by the structure analysis (Pritchard et al. 2000).
The criteria for detecting the most likely K was the Δ K, an ad hoc quantification related to the change of a second order in the logarithmic probability of the data in relation to the number of groups inferred by the Structure algorithm [ 32].
Δ K, an ad hoc quantity related to the second order change of the log probability of data with respect to the number of clusters inferred by the Structure program, proved an useful method for identifying a more probably true value of K when there was no previous model or a pre-defined number of groups to rely on.
Structure was used to infer the genetic structure; the model-based clustering algorithm implemented in Structure identifies clusters and subclusters by allelic frequencies.
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