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The aim of mucosal vaccines is to induce broad potent protective immunity by specific neutralizing antibodies at mucosal surfaces and by induction of cellular immunity.
We identify a major transcription pattern that represents a contraction of signaling networks accompanied by induction of cellular proliferation and protein metabolism, which is essential for full transformation.
Prolonged activation of HSC causes fibrosis and during fibrosis regression the number of these cells is greatly reduced by induction of cellular senescence and apoptosis and return to quiescent state [ 76].
Taking together these findings, it is speculated that YM529 exerts its anti-proliferative effect against NSCLC by induction of cellular apoptosis through the small GTP-binding proteins associated signal transduction pathway.
The contraction in the signaling network during the process of transformation was accompanied by induction of cellular proliferation and protein metabolism, whereas the expression of the ATP generating pathways remained unchanged.
It is possible that in response to infestation, plants in which the JA synthesis rate is somehow disturbed (either from a lack of JA in aos or an overproduction of JA-related compounds in fou2) try to compensate for unbalanced JA signalling by induction of cellular transport.
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Krueger, A. et al. HTLV-1 Tax protects against CD95-mediated apoptosis by induction of the cellular FLICE-inhibitory protein (c-FLIP).
In this cell background, inducible Rta modulated the levels of signature G1 arrest proteins, followed by induction of the cellular senescence marker, SA-β-Gal.
Transforming growth factor β3 (TGFβ3) has been shown to play a key role in this process via multiple synergistic effects including stimulation of initial adhesion of the palatal shelves, increasing the surface area of the MEE by the induction of cellular bulges and filopodia and by promoting MEE degeneration (13, 14, 17– 22).
The mechanism has been explained by the induction of cellular differentiation and impairment of stem cell function by decreased methylation due to reduced expression of Dnmt1 [ 141, 145].
8 Thus, this chemokine can regulate inflammation by both induction of cellular migration and promotion of a Th1/Th17 response.
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by induction of general
by transduction of cellular
by evaluation of cellular
by modulation of cellular
by depletion of cellular
by modification of cellular
by accumulation of cellular
by induction of gangrenous
by mean of cellular
by decrease of cellular
by inhibition of cellular
by interaction of cellular
by recruitment of cellular
by loss of cellular
by induction of erythritol
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