Sentence examples for by inducing conformational changes from inspiring English sources
Moreover, CD8 seems to help recognition of the specific MHC-peptide complex either by guiding an energetically favourable docking of TCR onto MHC, or by inducing conformational changes in the MHC complex that can augment the TCR/MHC-peptide interaction.
Our findings indicate that in vivo neddylation functions by inducing conformational changes in the C-terminal domain of Cul2 and Cul3 that free the RING domain of Rbx1 and bridge the gap for ubiquitin transfer onto the substrate.
Heparin activates antithrombin both by inducing conformational changes in the protein that specifically enhances factor Xa binding and by providing a surface to promote thrombin or factor Xa binding alongside antithrombin in a ternary bridging complex.
This review focuses on our current understanding of the role of the SWI/SNF ATP-dependent chromatin-remodeling complex in the activation of the myogenic program, by inducing conformational changes permissive for muscle-gene expression.
This is achieved by inducing conformational changes in the substrate protein, leading to events such as the activation of signaling cascades [1].
transmission of the stimulus by inducing conformational changes of the receptor iii.
The positive role of TCF acetylation in Wnt signaling is further supported by a recent study showing that human TCF4E2 can be acetylated at lysine 150 by CBP, leading to relief of transcriptional repression by transcription repressor presumably by inducing conformational change of TCF DNA complex [ 116].
A recent study has given new insights into the molecular arrangement of RuvBL1 and RuvBL2 and strongly suggested that in vivo activities are regulated by cofactors inducing conformational changes via domain II in order to modulate the enzyme complex into its active state.
Upon ligand binding, receptor-mediated activation of the MAPKKK can proceed through direct or indirect phosphorylation (through a mitogen-activated protein kinase kinase kinase kinase (MAPKKKK), or by a physically induced conformational changes [ 6].
Absorption of photons by the chromophore induces conformational changes in the channel that allow for the passage of cations across the cell membrane in which it is expressed (Boyden et al., 2005).
BPC1 induces conformational changes by cooperative binding to purine-rich elements (GAGAn) present in the AGL11 regulatory sequence [ 39].
