Sentence examples for by inducing a type from inspiring English sources

DDX41 is a helicase known to induce antiviral and inflammatory responses by inducing a type I IFN innate immune response.

The lead "switch-control" inhibitor, DCC-2036, potently inhibits both unphosphorylated and phosphorylated ABL1 by inducing a type II inactive conformation, and retains efficacy against the majority of clinically relevant CML-resistance mutants, including T315I.

Ectopic expression of the transcriptional complex has been shown to reprogram adult skeletal muscles by inducing a fibre type transition from the slow (type I) to the fast type (type II) (87).

Taken together, our results demonstrate that PKI-587 could act in HNSCC cells by inducing a different type of cell death.

Activation of the immune response and inflammation may also support tumor formation by inducing a Th2-type response [ 34].

The synergy of TLR3 with multiple host RNA sensors such as RIG-I and MDA5 is indispensable for specific interactions with viral dsRNA to restrict CHIKV replication by inducing a rapid anti-viral type I IFN response together with pro-inflammatory gene expression (Fig 8).

The polyphenol agonists act directly on the γδ T cell, and other cell types, by inducing a priming response, typified by up-regulation of activation markers and an increased responsiveness to secondary stimuli [1].

It was reported in 2005 that infection of macrophages by Theiler's murine encephalomyelitis virus induces a type of demyelination in mice that that that resembles human MS, and also observed induction of ATF2 30 minutes after the infection of macrophages [271].

This study indicates that leptin plays a proinflammatory role, in synergy with IL-1, by inducing NOS type II through a signalling pathway that involves JAK2, PI3K, MEK-1 and p38 kinase.

We have previously shown that dunce was required throughout development in order to rescue attention-like defects in the adult by inducing wild-type dunce in a mutant background in larvae (induction in the adult did not rescue the defects [3]).

The results indicated an indirect genotoxic effect by inducing different types of chromosomal abnormalities, likely sticky, disoriented and fragmented chromosomes.