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However, metformin protects against cisplatin cytotoxicity by inducing a reducing intracellular environment leading to lower cisplatin-DNA adduct formation.
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In patients with HF, it is known that left bundle branch block can cause LV diastolic dyssynchrony and marked diastolic LV filling impairment by inducing a reduced diastolic filling rate, and prolonged isovolumetric contraction and relaxation times.
The method relies on the use of low concentrations of reductants under net oxidizing conditions, arguably by inducing a locally reducing environment on the catalyst surface through different chemical mechanisms.
Synthetic colloids may exert this effect by inducing a decrease in erythrocyte aggregation, thereby reducing the low-shear viscosity of the blood [ 30].
The second group of anti-estrogen drugs (that is, SERDs) acts by inducing a conformational change of ER that reduces the ability of ER to modulate gene transcription and promotes ER for degradation by the proteasome [ 18, 19].
For example, smooth muscle relaxation can occur by agents that reduce myoplasmic Ca2+ by inducing hyperpolarization, reducing Ca2+ influx without changes in membrane potential, increasing Ca2+ efflux, or by reducing Ca2+ release from the internal store.
In view of these findings, estrogen inhibits osteoclast formation by inducing apoptosis and reducing osteoclast lifespan.
However, it is still unclear whether this positive change was induced by a reduced sitting time or the increase in total PA and MVPA.
By inducing China to reduce the role of its state-owned enterprises as a condition for joining TPP, we can help China avoid "the middle income trap" and further empower the growing middle class that will be an ally for a continuing "peaceful rise" and against counter-productive aggressive behavior.
Widespread uptake of an effective rotavirus vaccine could reduce maternal antibody levels by inducing herd immunity and reducing adult infections.
Provided the oxide film is present on the surface, we focus now on the changes of the film's structure (particularly nanostructure) induced by interaction with a reducing agent (carbon monoxide (CO)).
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