Sentence examples for by increasing the sequencing from inspiring English sources

These problems may be ameliorated by increasing the sequencing depth and by improving the taxonomic assignment of the sequences.

Thus, in our study, the reduction of background noise and increase in detection sensitivity by increasing the sequencing depth of the method led to the same results.

This bias is independent of the sequencing platform and cannot be avoided nor removed by increasing the sequencing coverage or the length of the reads.

Although the read-coverage is generally not complete for genes expressed at lower levels these gaps could potentially be filled by increasing the sequencing depth.

The 454 pyrosequencing single-end shotgun data presented difficulties that would, in several cases, not have been ameliorated by increasing the sequencing coverage (Additional file 1: Figure S1D).

A large number of repeats makes genome assembly difficult and cannot be resolved simply by increasing the sequencing depth e.g. using the next-generation low-cost sequencing platforms, due in large part to their short read lengths [ 36].

By increasing the sequence depth of the samples the overlap between NEs for snap frozen and FFPE DNA increases, suggesting that with an increase of sequence coverage the rate of false positive calls in FFPE can be minimized (Supplementary Figure S3).

This was empirically determined by increasing the sequence coverage 2.5-fold (to 43.5-fold total coverage) on the P-SSP7 WGSL library; this reduced the number of viral-contigs in the assembly (from 7 to 4), but did not improve the coverage bias (Figure 3).

We show that sensitivity decreases with decreasing base calling quality towards the ends of sequence reads which can be compensated for by increasing the sequence coverage in the ends.

As revealed in Table  4, the difference in the STMs computed using the CSSBN and an analytical CSPBN approach is significantly reduced by increasing the sequence length L. However, the inaccuracies, due to the inherent stochastic fluctuations in stochastic computation, are generally small and thus negligible.

Therefore they represent overlapping regions between both single enzyme datasets and could most likely also be identified separately by increasing the initial sequencing coverage per enzyme dataset.