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The new procedure uses an increased target cell population to assess chemical-induced damage by increasing the initial seeding density and by delaying the initiation time of chemical treatment.
We initially modelled UCH-L1 overexpression by increasing the initial amount of UCH-L1 and the synthesis rate by a factor of 2 and used an SBML event structure to decrease the rate of proteasome degradation by 70% after 20 hours.
It is noteworthy that by increasing the initial axial load the biaxial demand decreases.
The results illustrated that fluoride adsorption capacity was decreased, by increasing the initial fluoride concentration.
As shown in Fig. 4, by increasing the initial concentration of diazinon, the removal efficiency decreased.
While the rate of degradation is decreased by increasing the initial dye concentration.
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What is more, this method can be easily scaled up by simply increasing the initial amount of the starting material.
This phenomenon can be explained by the fact that increasing the initial concentration of dye leads to an increase in the number of molecules of (AO7), while the number of the radical's hydroxyls remains constant (H2O2 concentration and catalyst kept constant), thereby causing a decrease in the discoloration efficiency [19, 27].
By increasing the number of initial molecules, the number of states of the CME will quickly increase, hence rendering infeasible its analytical approach.
The metal uptake also increased by increasing the pH and the initial lead concentration.
The dwell time was kept at 0.1 ms. The threshold fluence was obtained by increasing the laser power until the initial point of ablation obtained.
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