Sentence examples for by increasing the binding from inspiring English sources
Notch inhibition modulates transcriptional programs involved in cardiomyocyte differentiation and development by increasing the binding of transcription factor Mef2c to cardiac loci promoters (Abad et al., 2017).
Conclusion: PRPr increases the neutrophilic phagocytosis of complement-coated particles through the action of ATP and ADP by increasing the binding avidity with iC3b, but not the number of Mac-1 (CD11b/CD18).
Recently, it was reported that increased tubulin acetylation in neurons could promote polarized transport of the kinesin-1 cargo protein JNK-interacting Protein 1 (JIP-1) by increasing the binding of kinesin-1 to acetylated tubulin [4].
Furthermore, the calculation of Kb for clozapine demonstrates that the intracellularly located point mutation affects the extracellular binding for clozapine via two mechanisms: either directly by increasing the binding affinity and/or indirectly by decreasing the EC50 for 5-HT.
Thus, TGF-β may prevent CAK action by increasing the binding of p27 to cyclin E-cdk2.
Glucocorticoid is reported to increase mitochondrial gene expression and OXPHOS activity by increasing the binding of GR to mtDNA [ 14].
Molecular imprinting efficiently promoted a better sensing signal by increasing the binding-affinity and substrate-selectivity towards the template molecule, compared with the control polymer prepared in its absence.
In extension, for wild-type proteins binding in weakly populated conformations, the same approach could be used to significantly raise the binding affinity by increasing the binding-compatible population.
The aforementioned limitations of AC can be addressed by increasing the forward binding rate constant of reactions, but the binding rate constant is often difficult to improve upon.
We found that the loop transposition could enhance the reaction rate obviously by increasing the hemin binding affinity to G-quadruplex.
We recently reported that PLD enhances expression of the MMP-2 gene by increasing the DNA binding activity of NFκB and Sp1, and then promotes glioma cell invasion [13].
