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Recent climate change has been characterised both by increased warming and by increased frequency of 'extreme events'.
NR1-deficient DRG neurons show increased excitability, as indicated by increased frequency of action potentials, and enhanced excitatory synaptic transmission in spinal cord slices, as indicated by increased frequency of miniature EPSCs.
The initial stages in the case of speciation would be characterised by increased frequency of mutation, which over several generations would decline as integrity of replication increased and the new home attractor increased in robustness, both features that would be subject to selection for fitness.
"Of course, there now is a problem obviously created by increased frequency of flights.
The chronic myocarditis is accompanied by increased frequency of peripheral CCR5+LFA-1+ T lymphocytes.
The relevance of rapid eye movement (REM) sleep in affective disorders originates from its well-known abnormalities in depressed patients, who display disinhibition of REM sleep reflected by increased frequency of rapid eye movements (REM density).
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These mice displayed high mutation rates accompanied by increased frequencies of colorectal adenomas and carcinomas [ 16].
This is paralleled by increased frequencies of both CD4+ and CD8+ T cells and higher expression levels of interleukin 2 and interferon γ at the tumor site.
The latter assumption is in line with the observation that only mice homozygous for mutant POLE develop a mutator phenotype accompanied by increased frequencies of tumor formation [ 16].
Chromosome instability (CIN) is characterized by increased frequencies of numerical and structural chromosomal aberrations (Lengauer et al. 1998) and is prevalent within a large fraction of tumor types.
UNICEF is requesting US$1.1 million in 2011 to continue its work on improving the delivery, speed and coordination of emergency and risk reduction programmes in a region characterized by increased frequency and intensity of natural and human-made disasters.
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CEO of Professional Science Editing for Scientists @ prosciediting.com