Sentence examples for by increased expression levels from inspiring English sources

The protein folding and membrane localisation seems to be unaffected by increased expression levels.

Most resistant metastases showed reactivation of the MAPK pathway, determined by increased expression levels of both p-ERK and p-MEK, although some variation was observed among different metastases.

In particular, already within 7 days of cell medium supplementation with all- trans-retinoic acid, neuroblastoma-derived cells show a neuron-like phenotype (Chambaut-Guérin et al., 1995), as confirmed by increased expression levels of the specific differentiation markers GAP-43 (Silvagno et al., 2002), NF-200, and NeuN (Redova et al., 2010).

However, this MG132-induced increase in ACh release was presumably caused by increased expression levels of proteins necessary for ACh synthesis/release and was independent from the misfolded SOD1-induced effect (Supplementary Material, Figs S4B and C).

These changes were paralleled by increased expression levels of CD36.

As an important apoptotic signal, the tumor suppressor p53 was activated as indicated by increased expression levels, DNA binding activity, expression of its target genes, and moreover, translocation to mitochondria [20], [22].

Unlike CSP deficient mice [27], CHL1−/− mice do not exhibit gross neurodegenerative changes [2], suggesting that CHL1−/− mice compensate for abnormal function of Hsc70, CSP, and αSGT by increasing expression levels of these proteins (Fig. S2, [7]).

It was thus concluded that SR-A promotes osteoclastogenesis by increasing expression levels of receptor activator of NF-κB (RANK) and related molecules [ 92].

The expression patterns of Clusters 2 and 3 are similar; Cluster 3 exhibits an immediate-early decrease in expression from BAC1 to BAC2 not seen in Cluster 2, followed by increasing expression levels through BAC5.

We have modified the Creator system by extending the multiple cloning sites of the donor vectors, creating a repository of downstream vectors, and by increasing expression levels with the Creator Splice system that allows for splicing at the 5' end.

The interaction of PD-1 with its ligands also affects the cell cycle, preventing progression through G1 phase by increasing expression levels of p15 and suppressing transcription of SKP2, a component of the ubiquitin ligase responsible for degrading p27 20.