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This paradox lies at the heart of how neurons can be killed by improper expression of a single aggregation-prone protein, how cancer cells can tolerate accumulating mutation burden, and how disease-associated mutations have devastating consequences in some individuals, but no effect in others.
However, synaptic pathology may also develop by improper expression of intra- and extra-cellular structural elements weakening synaptic stability.
Similar(58)
It is a shame to allow a good argument to be undermined by improper expression.
Most of the problems are caused by improper construction of utility networks and poor rehabilitation work.
Aberrant histone modifications may be caused by improper activities of histone-modifying enzymes, leading to inappropriate expression of tumorigenesis-related genes [ 5, 6].
This is caused by improper selection of SNI spectrum as the design major earthquake.
In addition to potential inaccuracies, Mr. Norris said false results might also be caused by improper execution of the tests.
Section 5 highlights the instability phenomena caused by improper design of damping resistor.
Alcohol dependence syndrome is insidious, taking years to be established, and is often preceded by improper use of alcohol [ 2].
Cracked nipples can be caused by improper positioning of the baby during nursing, improper latch of the baby onto the breast, soap residue on the breasts if improperly rinsed, as well as thrush (yeast infection of the breasts).
Cancer development is characterized by uncontrolled cell proliferation, which is in part due to expression alteration of genes which regulate cell growth and differentiation, such as the improper over-expression of oncogenes, or the under-expression or disabling of tumor suppressor genes [ 1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com