The endothelium imposes a structural barrier to the extravasation of systemically delivered oncolytic adenovirus (Ad).
We can conclude that the general CASE strategy utilizes processes to eliminate "superfluous" isomers from the full isomer set by imposing different structural constraints produced from the molecular spectra and a priori information (sample origin, chemical rules, etc).
We implement a method of evolutionary simulation that introduces site-specific rate variations in a natural way by imposing structural and functional constraints [ 21].
A decentralized controller for the nominal system is computed first by imposing structural constraints on the coefficient matrices gradually.
In her Corporate Crime Reporter interview, Ms. White's took the position that the S.E.C. and other regulatory agencies were better equipped to police corporations than prosecutors by imposing structural changes on organizations to ensure future compliance with the law.
By imposing some relatively mild structural conditions on f, H 1, H 2, and φ, one positive solution to the problem is ensured.
In 2013, Goodrich [28] proved that the nonlocal boundary value problem with mixed nonlinear boundary conditions − y ″ ( t ) = f ( t, y ( t ) ), 0 < t < 1, y ( 0 ) = H 1 ( φ ( y ) ) + ∫ E H 2 ( s, y ( s ) ) d s, y ( 1 ) = 0, has at least one positive solution by imposing some relatively mild structural conditions on f, H 1, H 2 and φ.
Strategies for the generation, preliminary design and structural optimization are proposed for the different patterns; in particular the optimization process is treated with mono-objective genetic algorithms, by minimizing the structural weight and imposing a constraint condition on the lateral stiffness of the building.
First, a common structural VAR model can be fitted to each subject individually by imposing the same zero constraints on the coefficients (thus defining the structure) while estimating the unconstrained coefficients for each patient separately.
This structural transition might impose a high degree of local structural constraints, which results in constraints on the protein sequence alongside requirements to be flexible.
