Sentence examples for by impairing the function from inspiring English sources

Tumor-derived EVs can contribute to creating an immunosuppressive microenvironment by impairing the function of immune cells.

Unfortunately, the cascade of inflammation directly injuries intestinal epithelial tight junction permeability [3], particularly for tumor necrosis factor alpha (TNFα) and high-mobility group protein 1 (HMGby) [4], by impairing the function of mitochondria [5, 6].

Biliary obstruction itself disadvantages the immune system and impairs its capability to fight infection, by impairing the function of certain immune system cells (neutrophil granulocytes) and modifying the levels of immune hormones (cytokines).

For example, halogenated anaesthetics inhibit the post-rest increase of contractile force by impairing the function of SR.

By impairing the function of the upper oesophagus sphincter, it may facilitate the reflux of bacteria from the gut.

(2001) showed that ERK inhibition caused the nuclear retention of vRNP complexes, by impairing the function of the viral nuclear export protein (NEP/NS2), and reduced viral production.

Adhesions are thought to cause symptoms by impairing the sealing function of the labrum or impinging against it.

Tubulin-binding agents (TBAs) such as taxanes and Vinca alkaloids act by impairing the normal function of mitotic spindles.

It is noteworthy that a long-term inhibition of HSP90 will affect mitotic progression by impairing the centrosomal functions [23], [24], [25].

C-kit mutations have been shown to induce ligand-independent (constitutive) CD117 phosphorylation and activation in human neoplasms, both by impairing the regulatory functions of the juxtamembrane domain and by directly targeting the kinase domain [ 31].

This process may also be amplified by UV exposure, impairing the functioning of biomolecules and eventually leading to less firm and less elastic skin that is more prone to wrinkling.