Cf. Ameriks 2003, or this passage from Łuków (1993, 221): "It is neither sufficient nor possible to prove law and freedom, but it is sufficient and possible to defend them by identifying the practical constraint which testifies to their instantiation in actual lives".
Identifying the constraints imposed by past adaptations is, however, of importance for understanding many questions in evolutionary biology, such as the evolution of host usage dynamics by multi-host viruses or the emergence of escape mutants that persist in the absence of antiviral treatments.
The algorithm starts by identifying the user-defined constraints, and applies those constraints on the nodes to extract only those nodes that satisfy them.
Alternatively, the GNG mismatches are corrected by identifying the minimal set of suppression constraints for reactions or transport mechanisms that lower the maximum biomass yield of the network below a pre-specified viability threshold.
As a result, we identified one valid model fulfilling all constraints (including the less conservative constraints obtained by identifying the basal- and hyperrepressed phenotype, see first row in Table S2, Additional file 1).
Travel surveys like the ones performed in more advanced countries can be a starting point to identify the constraints faced by low-income commuters (affordability, accessibility, etc).
To identify the constraints in the value chain. .
A novel algorithm is developed by dynamically identifying the binding constraints in the lower-level model.
The proposed method overcomes convergence issues encountered in alternate regression by identifying nonlinear constraints that restrict the search space to computationally feasible solutions.
A formative approach attempts to break the task-artefact cycle by identifying constraints that hold true regardless of actors or the specific instantiation of a particular design.
