Sentence examples for by identifying pathways that from inspiring English sources

Another challenge has been to unravel the underlying biological basis of toxicity by identifying pathways that ultimately link pollution-induced pulmonary and systemic oxidative stress with an associated risk of cardiovascular and obstructive pulmonary diseases.

The identification of enriched biological pathways shared between IB and CP, in the absence of any common associated genes, indicates that the connection between these two traits may be explained in part by genes located in the identified pathways that have yet to be adequately interrogated by investigators.

Contributing to policy debates on the appropriateness of conditions, this article sets out to investigate the overall buy-in of conditions by different stakeholders and to identify pathways that contribute to an acceptability of conditions.

By converging independent genomic datasets, we have identified pathways that have both biological function and genetic support to be important in PD.

This led us to explore signaling pathways related to Nek2 expression to identify pathways that are influenced by Nek2.

It is worth noting that our work can only identify pathways that are affected by a certain amount of drugs.

The aim of present study was to identify pathways that are regulated by autocrine IL-15 (IL-15R) in RASF.

We have supplemented this kind of analysis with a more global approach by gene set enrichment analysis (GSEA), to identify pathways that are differentially regulated in metastasizing and non-metastasizing tumors.

In order to identify pathways that are affected by E-cadherin inactivation, we performed a genome-wide expression study on 27 human mammary cell lines, which are well characterised on E-cadherin RNA and protein expression status.

However, other studies describe a downregulation of miR-125b and identify pathways that are regulated by miR-125b which rather imply tumor suppressive functions in those tumors (see Table  3).

To identify pathways that are affected by sarcoma-associated variants of HMGA2, we have over-expressed wild type and truncated HMGA2 protein in an immortalized mesenchymal stem-like cell (MSC) line, and investigated the localisation of these proteins and their effects on differentiation and gene expression patterns.