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We highlight the translational applications of our algorithm for drug discovery by identifying clusters of genes significantly enriched for single- and multi-drug cancer therapies.
Self-organization architectures can auto-classify large numbers (several thousands) of text documents by identifying clusters of documents in which members share common fingerprint patterns.
To provide complementary analyses, we began by identifying clusters of positive SNPs that fall within genes in each sample.
Based on all the preceding considerations, we modeled Cdk substrates by identifying clusters of both the canonical Cdk motif represented by the regular expression [ST]PX[RK] and a PSSM [Table 1] profile generated from Holmes and Solomon's kinetic data [28].
PFGE may contribute to the control of CR-BSIs by identifying clusters of microorganisms in neonatal ICUs, providing a means of determining potential cross-infection between patients.
The enzyme sequence diversity of the secondary metabolic pathways was examined by identifying clusters of segments associated with certain enzyme groups in the resulting map.
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Socrates works by efficiently identifying clusters of soft clipped alignments in the reference genome as candidate break points.
The software STRUCTURE 2.3.3 (Pritchard et al. 2000; Falush et al. 2003), which, by means of iterative algorithms, identifies clusters of related individuals from multi-locus genotypes, was used to examine the genetic structure of populations.
By applying the appropriate threshold, we identified clusters of similar earthquakes.
In addition, we studied the genomic distribution of the two statistics by means of spatial autocorrelation to identify clusters of markers showing strong differentiation and/or association with the phenotype.
On the other hand, unlike the above traditional clustering which uses all available conditions to cluster genes, biclustering has been introduced by Cheng and Church [ 5] to identify clusters of genes defined based on the respective subsets of conditions.
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