Exact(7)
However, a role for PTGDR in colon tumor growth is supported by human data.
At present this concept is only sparsely supported by human data [ 7].
Type I IFNs are important mediators of antiviral responses and their implication in the pathogenesis of T1D is supported by human data.
The criticism of mouse models in pre-eclampsia needs to stop, provided the animal data are backed up by human data as illustrated in a number of comprehensive studies (Maynard et al., 2003; Wang et al., 2013).
Increase in the number of Th17 cells is considered as a part of the pathogenesis of diabetes, and it has been supported by findings in type 1 DM murine model and by human data [ 17, 18].
However, ribavirin is contraindicated in pregnancy because of its teratogenic effects, which have been documented in multiple animal studies up to 7 months after cessation of treatment (20 ), but these findings are unsupported by human data.
Similar(53)
For the examples discussed above, evidence for a causal relationship between specific early indicators and adverse outcomes is provided by experimental evidence in animals and supported by observational human data.
With our recent scientific breakthrough represented by our human data showing the powerful killing effect of T cells generated by our cervical dysplasia therapeutic vaccine, we are encouraged by the published preclinical results generated by our therapeutic vaccine against HBV.
We applied the modulePreservation R function to assess whether modules defined by the human data were preserved in C57BL/6.NOD- Aec1Aec2 mice, Sjögren's syndrome-like disease model datasets.
Prompted by these human data we performed an association study and found a significant association of promotor SNP (rs12403575) with FS and mTLE.
Once again, the smaller dynamical range covered by the human data (see dashed lines in Figure 9) makes a precise interpretation of the results more difficulty.
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