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ESCs cultured in normal serum-based medium with leukemia inhibitory factor (LIF) retained the pluripotent state as indicated by high expression levels of Cdh1, Fbxo15, and Rex1 (Fig. 4a, +LIF).
This inhibition was enhanced by low, but dampened by high, expression levels of L7A and L7B and differences were observed between the two isoforms.
Some miRNAs, known as oncomiR, show different expression levels in cancer and are capable to effect on cellular transformation, carcinogenesis and metastasis and are characterized by high expression levels in tumors compared to normal tissues.
The study was performed in female mice at the late stage of malignancy, which is characterized by high expression levels of VEGFR-2, CD31, and other proangiogenic factors in the mammary tumor vasculature [29].
The MIB1/HERV16 segment is located between the Mamu-B*12 and B*38 gene, and is characterized by high expression levels, the latter being the most centromerically situated B gene with characteristics of a major.
This cytokine mixture was recently found to be optimal for induction of a psoriatic phenotype in vitro, as witnessed by high expression levels of CK16, SKALP/elafin and hBD-2 [36].
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Angiogenesis in the tumor was frequently observed as demonstrated by high expression level of vascular endothelial growth factor receptor-2 (VEGFR2) (Flk-1) in tumor vessels.
All of these cell lines were characterized by high expression level of ganglioside GD2 with the highest expression level in EL-4 lymphoma cells.
Because highly expressed genes have generated more PPs, the intron loss frequency and PP abundance are linked together superficially by high expression level.
For all subjects studied, the memory subset of CD4+ T cells showed significantly higher expression levels of APOBEC3G, TRIM5α, and LEDGF/p75, while the CD16+ subset of monocytes was characterized by higher expression levels of LEDGF/p75.
Compared with COL scaffold, cells on COL-nanofiber scaffold exhibited more robust osteogenic differentiation, indicated by higher expression levels of OCN and runx2 genes as well as the accumulation of calcium nodules.
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