Sentence examples for by global expression profiles from inspiring English sources

Clusters generated by global expression profiles partitioned samples in well-distinguished subgroups that overlapped with clusters obtained using "biologic scores" (cytohistologic variables) and differed from clusters based on "technical scores" (RNA/complementary RNA/microarray quality).

Although it is not easy to distinguish the primary or secondary target genes by global expression profiling alone, the meta-analysis of the combined data sets of global ChIP assays and global expression profiling were able to dissect the downstream gene regulatory network of Oct3/4 as summarized in Figure 3 and 4 (see a complete list in Supplemental Table S8).

The prediction of similar tumor type by global expression profile is consistent with the phenotypes of the transgenic mice.

Our results demonstrate the feasibility of utilizing biomarkers discovered by global expression profiling analyses for the detection and diagnosis of OTSCC.

We demonstrated that C2mE-related transgenic mice show significant similarity to intestinal-type gastric cancer when analyzed by global expression profiling.

These functional assays serve to test and confirm the consequences of mTOR activation predicted by global expression profiling of a previous independent set of BPA-exposed HRBECs (24).

The present study indicated that human intestinal-type gastric cancers exhibited significant similarity to C2mE-related mice, especially to K19-Wnt1/C2mE K19-Wnt1/C2mEl expression profiling.

Using overexpression of miRNAs followed by global expression profiling using microarrays, they demonstrated a modest but significant downregulation of mRNA levels of genes that were enriched for the miRNA seed sequence.

By combined analysis of global expression profiles and pimonidazole data, a comprehensive picture of the transcriptional programme in pimonidazole-positive tumours can be achieved.

In 2006, Neve et al. [ 19] identified two major groups (basal and luminal) in a panel of ~50 breast cancer cell lines by independently comparing the global expression profiles of cell lines and primary breast tumors.

Associations between start sites with similar chromatin patterns are validated by significant correlations in their global expression profiles.