Sentence examples for by genome engineering of from inspiring English sources
This article provides a survey of our knowledge of genetic transfer processes among thermophiles, of mechanisms for chromosome stability at high temperatures, and of efforts to enhance biofuel production by genome engineering of thermophiles.
We discuss the unanswered questions posed by genome engineering experiments in a variety of systems in which the serine recombinases have been used and finally describe more recently discovered serine recombinases that have the potential to be used in genome engineering.
This method could provide a paradigm shift by making large-scale genome engineering of many thousands of targets available as a standard tool for strain optimization and other projects where large-scale targeted mutagenesis searches are needed.
Our multiplexed approach holds great potential for robust genome engineering of industrial actinomycetes and novel drug discovery by genome mining.
Thus genome engineering of CHO cells for improved product quality and yield is of great interest.
Generating deletions (such as in this study) and concomitantly creating insertions by HR may be another genome engineering approach of value for basic research and crop improvement.
In addition to generating mutants, the DSBs produced by Cas9/sgRNA enable several other applications of genome engineering, including insertion of exogenous DNA through homologous recombination (Katic and Grosshans 2013; Tzur et al. 2013), and are likely to become an important tool for C. elegans researchers.
Thank you for sending your work entitled "Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery" for consideration at eLife.
Finally, this review will provide a perspective on the immediate challenges and opportunities foreseen by the use of CRISPR/Cas9 genome engineering and regulation in the context of metabolic engineering.
We confirmed the RNAi phenotype by generating FAT1 mutant cell lines by CRISPR/Cas9-mediated genome engineering.
