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Otherwise, at least some of the gap-filling gene candidates predicted by genome context analysis would have shared no homology with previously known components from the collection.
Such gaps were filled-in by the most likely gene candidates revealed by genome context analysis (e.g. those functionally coupled with canonical genes of the respective pathways via operons and/or regulons).
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I have no concerns about the quality of sequence comparison, domain definition and genome context analysis.
Genome context analysis was performed using the NCBI Genome Workbench and scrutinized manually.
Genome context analysis suggests that the archaeal RPC34 homologue is involved in RNA metabolism.
Recently, our group conducted systematic genome comparisons and genome context analysis on fully sequenced prokaryotic genomes to detect restriction modification-linked genome restriction modification-linked
We present the Microbial Genomic context Viewer (MGcV), an interactive, web-based application tailored to strengthen the practice of manual comparative genome context analysis for bacteria.
The genome context analysis does support the idea of separate functional groups for LAM and YjeK proteins.
Genome context analysis of the regions flanking the orc/cdc6-associated replication origins was performed using the NCBI Genome Workbench and scrutinized manually.
Genome context analysis supports a function of this archaeal protein in the transcription of non-coding RNAs.
For the gene encoding DVU1949 regulator, genome context analysis indicated a co-transcription with orthologs of DVU1952 gene encoding a hypothetical protein in seven Desulfovibrionales genomes.
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