Sentence examples for by generating the vasoactive from inspiring English sources
ACE contributes to blood pressure regulation by generating the vasoactive octapeptide angiotensin II from inactive decapeptide angiotensin I and by cleaving the vasodilator bradykinin.
We showed previously that the neuropeptide vasoactive intestinal peptide (VIP) suppresses innate immune responses, modulates adaptive responses by generating regulatory T cells (Treg) through the induction of tolerogenic DCs (tDCs), and has therapeutic effects in models of autoimmune/inflammatory disorders.
It is the substrate of renin, the rate-limiting enzyme of the RAS enzymatic cascade that generates the decapeptide angiotensin I (AngI), which then becomes further processed to the functional vasoactive octapeptide AngII by activity of the angiotensin I converting enzyme (ACE).
ETRs are class A G-protein-coupled receptors (GPCRs) activated by the vasoactive peptide hormones endothelins1.
Inhibition of inflammatory pathways induced by the vasoactive factor angiotensin II also improves vascular functions in RA patients.
The present studies evaluated whether increasing the level of hypoxia in the tumour tissue, by treatment with the vasoactive agent hydralazine, could modify the chemosensitising ability of nitroheterocyclics.
As a compound it is rapidly metabolized by endopeptidases to form the vasoactive lysine vasopressin.
Independent predictors of mortality were the initial severity assessed by the GMSPS (p = 0.001) and use of high doses of vasoactive drugs evaluated by the vasoactive-inotropic score (p = 0.026).
In the present study the use of vasoactive drugs did not significantly differ between patients with RDRI above or below 0.7, as documented by the vasoactive-inotropic score (VIS) calculated for each patient at each measurement.
12 Placentae express receptors for melatonin 13 and thus melatonin may protect against oxidative stress generated by the dysfunctional organ, thereby inhibiting the release of vasoactive factors responsible for the clinical syndrome of pre-eclampsia.
This view of ADE emphasizes the role that viral replication plays in generating pro-inflammatory and vasoactive factors.
