Sentence examples for by generating the stable from inspiring English sources
By generating the stable transgenic zebrafish lines that expresses zProgerin as well as by transiently manipulating the LMNA-MOs in early developmental stages of zebrafish embryos, premature aging can now be assumed to be adequately modeled in this system.
We confirmed the enhancer activity of these five HCNRs by generating different stable zebrafish transgenic lines for each region by using the same Xenopus genomic sequences.
Methods: In view of these findings, we examined the role of β3 in pancreatic cancer by generating two stable β3-expressing pancreatic human cell lines and characterizing their behavior in vitro and in vivo.
We modelled the disease here by generating stable cell lines expressing disease-associated mutants.
Arboleda and colleagues approached this by generating stable breast and ovarian cancer cell lines expressing the full-length Akt2 cDNA.
In order to investigate the role of NPHP1 in these functions, we used MDCK cells overexpressing PC-1, and we achieved silencing of NPHP1 by generating stable transfectants carrying a shRNA directed against canine NPHP1 (sh1 or sh2).
We initiated our analysis by generating stable Tcf-4 overexpressing MCF10AT cells (Dawson et al, 1996).
We addressed these questions by generating stable transfected PC12 lines that conditionally express wild-type, S52R and G392E neuroserpin.
We investigated this possibility, by generating stable MM cell line-derived clones expressing a cyclin D1-green fluorescent protein (GFP) fusion protein (D1-GFP) or GFP alone.
We sought to determine whether each SEPT9 isoform has similar intracellular distribution by generating stable MCF7 clones, each expressing one GFP-tagged SEPT9 isoform (Additional file 4, Supplementary Figure S3).
We next investigated whether Dali regulates neural differentiation by generating three independent stable Dali knockdown N2A cell lines each showing approximately 50 70% reduction of Dali transcript levels and inducing neural differentiation using RA.
