Sentence examples for by generating the repressive from inspiring English sources

In HF-SCs, PcG represses hair follicle differentiation by generating the repressive H3K27me3 mark at TSSs of key differentiation genes, which are repressed in HF-SCs, but expressed in HF-TAs.

H3K27 is trimethylated by the polycomb repressive complex 2 (PRC2) to generate the repressive H3K27me3 mark.

GSCs mutant for eggless (egg), a HMT that generates the repressive H3K9me3 modification, display both maintenance and differentiation defects [ 36].

Consistently, Pasini et al. reported that RBP2 associates with the important Polycomb repressive complex 2 (PRC2), which enzymatically generates the repressive mark H3K27me3 for silencing of many differentiation-specific genes in ES cells [ 140].

Polycomb-group (PcG) proteins, which were first discovered in fruit flies, contribute to the repressed state of crucial developmental or lineage-specific regulators by generating a repressive histone mark.

HMCan also showed superior results on a ChIP-seq dataset generated for the repressive histone mark H3K27me3 in a bladder cancer cell line.

On the experimental ChIP-seq dataset generated for the repressive mark H3K27me3 in the CL1207 human bladder transitional cell carcinoma cell line, peaks in proximity of gene TSSs that were detected only by HMCan corresponded to lower gene expression compared with the peaks detected only by CCAT.

To further verify the repressive role of vosA in conidiation, we generated the vosA overexpression mutant by fusing the vosA ORF with the inducible alcA promoter [25].

The mutation in 59A may act by modulating the repressive activity or degradation of Cup9p.

The autonomous-pathway represses FLC expression partly through generating repressive histone modifications in FLC chromatin.

Eventually, neural precursors are selected by the repressive activity of E spl) bHLH proteins [ 55, 56].