Sentence examples for by generating libraries of from inspiring English sources

The natural process of exon shuffling can be mimicked in vitro by generating libraries of exon-shuffled genes and subsequently screening target DNA from libraries [162].

We investigated the effect of size on chemical similarity algorithm performance by generating libraries of hypothetical natural products of fixed sizes.

The synthesis of ABT-199-BODIPY is convergent; it would be possible to test other modifications by generating libraries of aryl sulfonamides (accessible in 2 3 steps from commercially available materials) and coupling to intermediate acid 1. ABT-199-BODIPY was obtained in ca. 9% overall yield over the longest linear sequence.

T4 Rnl2 is now commonly used in RNA research, notably for the identification of small RNAs by generating libraries for sequencing with high-throughput sequencing technology.

The degree of bias was assessed by generating libraries from a pool of 20 nt RNAs of known composition using each protocol and sequencing them on an Ion Torrent personal genome machine.

The efficiency of this protocol allows generating libraries of recombinant genes by combining in one reaction several fragment sets prepared from different parental templates.

First, we conduct a simple proof-of-concept validation of the LEMONS approach, by using LEMONS to generate libraries of short, linear proteinogenic peptides.

Having considered the impact of a number of biosynthetic features on chemical similarity search, we finally sought to quantify the performance of each chemical similarity method by generating realistic libraries of extensively tailored natural products, and thereby derive general recommendations for similarity search in modular natural product chemical space.

However, it is virtually impossible to exploit all individual wild accessions by generating genetic libraries of ILs, considering >75 000 Solanum accessions are conserved in genebanks around the world (Larry and Joanne, 2007).

Given the high-throughput nature of this technology, it would be possible to screen large regions of non-coding DNA for transcriptional activity by generating a library of reporters from tiled PCR products.

A global approach to characterise in silico predicted GpiPs has been initiated by generating a library of 45 mutants.