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We have tested this hypothesis by generating and analyzing a mouse strain that lacks the gene encoding the essential subunit of the N-methyl-d-aspartate (NMDA) receptor NR1, specifically in dentate gyrus granule cells.
We have tested this hypothesis by generating and analyzing a genetically engineered mouse strain in which theN-methyl-d-asparate (NMDA) receptor gene is ablated specifically in the CA3 pyramidal cells of adult mice.
The utility of our ET cassette-labeled primers is demonstrated by performing four-color capillary electrophoresis sequencing with the M13 -21 M13 -21 primer and by generating and analyzing a set oforwarde-nucleotide-primerrphism-specific PCR andlicons.
Here we have tested the current models on Sei1 function by generating and analyzing Sei1-deficient cells and mice.
Here, we addressed the role of FoxM1 in T cell development by generating and analyzing two different lines of T-cell specific FoxM1 deficient mice.
We decided to further characterize the in vivo function of TWINKLE by generating and analyzing conditional Twinkle knockout mice.
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To confirm the results obtained by RNAi, we generated and analyzed MARCM clones deficient for BMP signaling.
In this study, to test this hypothesis of non-cell autonomous effects by glial cells as well as by stem/progenitor cells, we generated and analyzed phenotypes of Drosophila models expressing human mutant Htt or Atx1 in the glial cell lineage at different stages of differentiation.
They relied on a genome-wide technique called parallel analysis of RNA ends (PARE) or degradome sequencing, where mRNA fragments bearing 5′ monophosphate termini are specifically selected by adaptor ligation and short sequence tags representing their 5′ ends are generated and analyzed by high-throughput sequencing.
To investigate the performance of SI, NPCI and CIM-NPCI methods for estimating positional confidence for QTL detected by CIM, 4,000 RI1 data sets each simulating four equivalent and moderate QTL effects were generated and analyzed by all three methods.
For each sample size, 100 datasets were generated and analyzed by IgC2N.
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by generating and investigating
by generating and testing
by generating and considering
by generating and annotating
by generating and applying
by generating and maintaining
by generating and installing
by visualizing and analyzing
by preparing and analyzing
by generating and characterizing
by generating and storing
by generating and incorporating
by generating and removing
by sampling and analyzing
by monitoring and analyzing
by generating and controlling
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