The objective was to develop a method that would increase our understanding of the pathways involved in various traits and to detect the effects that would have been missed by traditional single-marker analysis without generating an excess of false-positive pathway associations.
Heather Wolf outperformed her colleagues by generating the most excess return of any analyst (excess return is defined as the difference between returns that an investor would have realized by following an analyst's advice and the industry's overall return over the same period).
In one sense, the blackout, the MSBlast worm and the SoBig virus circulating on the Internet this week were similar, causing disruption by generating excess traffic in systems that cannot handle it.
In his most recent letter to shareholders, Dimon boasted that JPMorgan Chase has spent "almost 55 billion" on stock buybacks over the past five years by "generating excess capital that we do not expect to use in the next few years". Stock buybacks flush money to shareholders rather than invest in or grow a company's operations.
Class 1 mutations are of several different types, but all work by generating excess amounts of cell membrane, which drives spontaneous shape changes and ultimately proliferation.
Therefore, it is unlikely that the excessive epidermal IC phenotype observed in mibta52b mutants is generated by an excess of cell proliferation.
This investigation provides new evidence for a model of osteolytic bone metastasis where constitutive secretion of noggin by cancer cells mediates inhibition of bone formation, thereby preventing repair of osteolytic lesions generated by an excess of osteoclast-mediated bone resorption.
We thus investigated the potential of the 3 agents to scavenge ROS production generated by an excess of hexacosanoic acid (C26:0), as measured using the probe dichlorofluorescein.
Given that the stress germination was conducted on pleated filter paper moistened with 60 ml of a NaCl/mannitol solution instead of 30 ml of deionized water, the observed gene expression changes might be related to hypoxia generated by an excess of liquid functioning as a diffusion barrier for oxygen.
Cu can also be a toxic element when present in excess by generating hydroxyl radicals that damage cells at the level of nucleic acids, proteins, and lipids or by reacting with thiols to displace other essential metals in proteins [ 4].
