The rotating impellers in the ULFED enhance gas transfer by generating an "active mixing" effect in the fiber bundle that improves convective mixing at gas exchange surfaces [24, 25, 47, 48].
Recruitment of histone modifying enzymes to one of these sites terminates heterochromatin spreading by generating an active chromatin conformation at the barrier.
In a second model, also corroborated by experimental evidence, it is instead proposed that AIF and CypA independently translocate in the nucleus, where they regulate chromatinolysis and programmed necrosis by generating an active DNA-degrading complex involving the H2AX as well.
We envision that this could be achieved by either increasing MOB1 phosphorylation by MST1/2, known to increase LATS1/2-MOB1 interactions[105], or by generating a MOB1-independent active LATS variant.
After removal of the N-terminal signal peptide, pro-chemerin is processed at the C-terminal end by serine proteases to generate an active pro-inflammatory adipokine, which can be cleaved further at its C-terminal end by cysteine proteases to generate an anti-inflammatory peptide [ 58].
With the catalyst having P/V ratio >1.0, the hydrolysis of the VPP surface under working conditions at temperatures higher than 340 350 °C, followed by the oxidation of vanadium, generates an active layer made of vanadium oxide and of P2O5/H2O.
Then, considering the nonlinear characteristics of the tire force and external disturbance, a robust yaw rate control method is designed by applying a steering motor to generate an active steering angle to adjust the yaw stability of the vehicle.
PERK activation paradoxically promotes transcription initiation of the gene encoding ATF4 even when eIF2α is substantially phosphorylated, leading to upregulation of CHOP Once activated by ER stress, ATF6 moves to the Golgi, where it is cleaved by S1P and S2P proteases to generate an active form that mediates transcriptional induction of ER-localized molecular chaperones and folding enzymes.
The latter is synthesized as an inactive form that is self-activated by cleavage, generating an enzymatically active heterodimer composed of 10 and 20 kDa chains [22].
By generating enzymatically active versus inactive isoforms, alternative splicing provides an excellent mechanism for fine-tuning the level of active caspases at the post-transcriptional level.
It was observed that laccase and peroxidases can act as starters of a chain reaction which leads to dye degradation by generating highly active free radicals (e.g., Mn3+, lipid, hydroxyl, and peroxy-radicals) [ 26, 27].
