Sentence examples for by gene expression microarray from inspiring English sources
Previously in an effort to understand FLCN function, we searched for differentially expressed genes in cells expressing mutant FLCN compared to wildtype FLCN by gene expression microarray analysis.
Analysis by gene expression microarray revealed a clear separation of gene signatures, with downstream activation of angiogenesis and down-regulation of genes involved in cell cycle regulation in SmoA1+/−; Pten +/− medulloblastomas.
In comparison, the genes Wnt3 and Wnt7a, which were found to be up-regulated by gene expression microarray analysis, were validated as up-regulated by real-time, RT-PCR and western blotting in SmoA1 +; Pten +/− medulloblastomas (Figure S1).
These PPIs are essential to sporulation but cannot be detected by gene expression microarray experiments.
The embryonic origin of these proteins was validated by gene expression microarray analysis.
Blood from this source was also used for the determination of rapamycin-regulated genes in lymphocytes by gene expression microarray.
The dynamic range of expression obtained by messenger RNA sequencing can be much broader than that obtained by gene expression microarrays, allowing the detection of rare transcripts and more precise quantitation of expressed transcripts.
Figure S1, S2, S3 shows that those transcripts are predominantly expressed in placental tissues as compared with the many other human tissues assessed by gene expression microarrays.
Thus, we were able to confirm that there is an important degree of loss of information when carrying out genome-wide studies by gene expression microarrays alone, and that this information can be recovered by the integration of epigenetic data, reflecting the additive benefit obtained from such an integrated approach.
