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In addition, as huntingtin is ubiquitously expressed, mutant huntingtin-specific changes could also be reflected by gene expression changes in blood.
We therefore undertook these translational studies to begin the development of a unique data set of human cellular responses to LDIR as measured by gene expression changes when exposure occurs to a normal tissue with its complex cellular mixture and three-dimensional architecture.
Moreover, we report that sex specific transcriptional patterns take place during gonadal developmental stages in the bivalve's tissues and that mussels' gonadal developing and maturation is driven by gene expression changes.
Here, we show that increased vulnerability to mitochondrial dysfunction and oxidative stress in an insulinoma cell line is associated with (1) morphologic change to a flat, surface-adherent phenotype accompanied by gene expression changes in integrin/FAK signaling pathways (Supplemental Figs.
That hepatotoxicity might ensue as a time-dependent secondary effect of hematotoxicity is supported by the observation [61] that mechanism of action of dinitrotoluenes on cytotoxicity of isolated rat hepatocytes in culture differs from any of the pathways implicated by gene expression changes in our whole animal exposures.
The development of multicellular organisms is accompanied by gene expression changes in differentiating cells.
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Users of these approaches usually assume that the signaling between proteins is reflected by gene expression change.
An increasing number of studies have reported that functional divergence in duplicated gene is accompanied by gene expression change although the evolution mechanism behind this process remains unclear.
Response to oxygen-containing compounds and bacteria were implicated by gene-expression changes at the earliest day 2 and latest, day 30 time-points.
We sought to better understand how LPA in the microenvironment impacts molecular ovarian cancer progression by examining gene expression changes induced by LPA in ovarian cancer cell lines.
By comparing gene expression changes induced by Sir2 overexpression and resveratrol in D. melanogaster we have shown for the first time a significant overlap between the two datasets.
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by gene frequency changes
by gene expression data
by gene expression profiles
by gene expression levels
by gene expression analyses
by protein expression changes
by gene expression signatures
by gene coexpression changes
by gene expression results
by gene expression experiments
by gene expression states
by gene expression studies
by gene expression arrays
by gene expression microarrays
by gene expression patterns
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