Sentence examples for by fusing the variable from inspiring English sources

Chimaeric Lym-1 (chLym-1) is a monoclonal antibody generated by fusing the variable region genes of murine Lym-1 to human γ1 and κ constant regions.

The antigen used in these studies comprises an Id-containing IgG obtained by genetically fusing the variable region of the patient's tumor-specific Id with a generic constant domain of a human IgG1, regardless of the original tumor isotype (IgG or IgM; antigens of the IgA isotype were not included in this study).

Rituximab was genetically engineered by fusing the murine variable regions of the anti-CD20 mAb 2B8 with the human IgG1 constant regions [14].

A FcR-binding deficient mutant of PDL241 (241-G2M3) was made by fusing the PDL241 variable domains to human IgG2M3 Fc domains [ 20].

The final HDR image (L hdr ) was obtained by fusing the best parts of each image.

The antibody was expressed from a large single chain (lsc) coding sequence, which consisted on the entire IgA heavy chain protein fused to the variable region of the light chain by a flexible linker peptide.

By repeating this process a number of trials and fusing the results by simple averaging, a more reliable importance measure is obtained for each candidate variable.

However, relatively little progress has been made in fusing the complementary information provided by these modalities.

First, by oligomerization of two or more TRAIL trimers or second by artificial cell surface immobilization, for example, by fusing soluble TRAIL to a single-chain variable fragment (scFv) of an antibody specific for a cell surface-exposed antigen.

The latter improvement was obtained by either fusing VHH recognizing different epitopes, but also by fusing multiple copies of the same VHH.

Fusing the two seems sensible.