Sentence examples for by functional divergence of from inspiring English sources

Much of the diversity of the chemoreceptor family has evolved through widespread and repeated whole-gene duplications, followed by functional divergence of those duplicates that do not degrade to pseudogenes [2], [3].

Our results show that anoctamin protein paralogs evolved from several gene duplication events followed by functional divergence of vertebrate anoctamins.

Gene duplication, the second kind of evolutionary event, is often followed by either silencing of one of the duplicated genes or by functional divergence of the duplicates.

Preservation of duplicate genes is promoted by functional divergence of paralogs, either by subfunction partitioning among paralogs or the acquisition of a novel function by one paralog.

The second kind of process consists of gene duplications followed by either silencing of one of the duplicated genes or by functional divergence of the duplicates [ 24- 26].

Such situation could likely results from a gene duplication event in a common ancestor followed by functional divergence of the paralogs.

It is generally accepted that gene duplication followed by functional divergence is one of the main sources of metabolic diversity.

Occurrence of large number of pseudogenes in ORs because of the event of loss of selection pressure and the process of gene duplication followed by functional divergence leads to the formation of multiple gene families and are two important phenomena when we deal with ORs in eukaryotes.

Our study establishes a paradigm by which functional divergence of pluripotent TFs from the normal SC state accompanies transformation and could therefore be used to develop therapies targeting somatic CSCs in aggressive tumors.

Gene duplication followed by the functional divergence of the resulting pair of paralogous proteins is a major force shaping molecular networks in living organisms.

A rate increase is predicted when gene duplication is followed by functional divergence and could occur because of positive Darwinian selection or an increase in fixation of neutral mutations as result of relaxation of functional constraints [ 37- 40].