Sentence examples for by functional characterization of from inspiring English sources
In order to keep the parental binding affinity, we resurfaced m357 in the variable regions of both the heavy and light chains via computer-aided molecular modeling followed by functional characterization of the humanized antibody.
Preliminary meta-analysis is underway which will be followed by functional characterization of the key hits, with a full report to be submitted soon.
Moreover, the annotations have to be continuously updated, since further information is available by functional characterization of the most interesting sequences.
It is tempting to speculate that Awi-Spherulin is functionally required to supply the energy necessary for the metabolically demanding process of biocalcification, however such a hypothesis awaits support by functional characterization of Awi-Spherulin.
The study presented here describes powering of this model for further vaccine and regimen improvements by detailed mapping of vaccine-induced T-cell specificities supported by functional characterization of the HIVconsv vaccine-induced cellular responses, which provides comprehensive and sensitive tools for further vaccine advances.
These TRIM proteins can block viral infection by different mechanisms, as revealed by the functional characterization of TRIM5α, TRIM19 and TRIM25.
While this manuscript was under evaluation, this prediction was fully confirmed by the functional characterization of the thalianol pathway by Fields and Osbourn [ 53].
This can be achieved by pinpointing crucial residues for interaction or by a functional characterization of the entire subdomain.
The genetic basis for disrupted mitochondrial integrity as a cause of neurodegeneration in PD was uncovered by the functional characterization of mutations that cause loss of Parkin or PINK1 function in autosomal recessive forms of the disease.
The only way for us to determine whether a given enzyme possesses the proposed activity is by functional characterization, which represents one of our future objectives.
In summary, this study performed with LCLs followed by functional characterization has enhanced our understanding of the action of gemcitabine and AraC in the therapy of cancer.
