Sentence examples for by functional aberrations in from inspiring English sources
Like other lymphoid cancers, CLL pathogenesis appears to be driven both by functional aberrations in immune function (Stevenson et al. 1998) and by somatic mutations, some of which may be a consequence of environmental exposures (Magrath 1992).
Other tests, including general health screen, sensorimotor functioning and gating, anxiety, social behaviour, learning and memory did not show any functional aberrations in Kv10.1 null mice.
At the synapse level, we demonstrated both morphological and functional aberrations in mouse and Drosophila models.
This biochemical TCR signalling deficit translated to functional aberrations of thymic development manifest by reduced thymocyte apoptosis in vivo following anti-CD3 injection, increased numbers of TCRlo thymocytes, and reduced numbers of peripheral CD4+ or CD8+ T cells.
However, characteristic functional aberrations were indicated by up-regulation of IGF-II, PAI-1 and PLOD-2.
The reasons for the functional aberration of P53 in melanoma described in the current study are unclear.
A common strategy to distinguish functional aberrations from passengers is to identify those aberrations that are recurrent across multiple samples.
Loss of cell cycle control through the structural or functional aberration of checkpoint genes and their products is a potentially important process in carcinogenesis.
These functional interactions suggest that loss of the TACC proteins may promote tumor progression by increasing aberrations in centrosomal duplication and function, or DNA damage responses [ 10, 53].
Collectively, our data revealed that Radix Astragali effectively protected against cardiac functional and morphological aberrations in experimental autoimmune myocarditis.
