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For chemical-based drugs, simply producing the active ingredient can take a dozen chemical reactions, followed by formulation and packaging.
Loading and release of INDO from filamentous structures was influenced by formulation composition; indicating potential to 'fine-tune' dosage forms.
Results obtained in this work showed that oral delivery of gentamicin was improved by formulation as surface modified SNEFs.
A new feature of our model is combining region matching and segmentation by formulation of the energy minimization problem with free boundary conditions.
Results obtained in this work showed that permeation of DNa through the cornea construct was improved by formulation as SLN modified with phospholipid.
The highest fine particle fraction was obtained by formulation containing spray dried drug and lactose (63 90 μm) as a carrier with drug/carrier ratio 2 1.
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This work shows how sex-by-formulation interaction can affect bioequivalence conclusions.
Over this parameter, a significant sex-by-formulation interaction was detected: 90CI CMAX T/R was 0.838 1.36 in women and 0.540 0.920 in men; with a 52% relative difference between point estimates.
The second problem is what is called subject-by-formulation interaction.
Endemic-area infants, like malaria-naïve adults, should be better protected by formulations that negligibly protect endemic-area adults.
Figure 3 shows the amount of drug released by formulations during the course of 24 h.
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