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In addition, we tested for the moderating effect of relevant covariates by fitting appropriate interaction terms in the model.
The effect of controlling for the possible confounding factors listed above was assessed and we also investigated whether associations differed by gender, parental occupation or education by fitting appropriate interaction terms to the models.
Tests for differences in the absolute treatment effect according to each characteristic (ie, tests for interaction) will be derived from standard tests for heterogeneity/trend across subgroups or, where needed, by fitting appropriate interaction terms with treatment allocation in a linear regression model.
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We fitted appropriate interaction terms to investigate whether risk of self harm in relation to diagnosis differed between men and women.
The uncertainty demonstrated by the divergence in expert opinion can be described by fitting appropriate probability distributions for probabilistic sensitivity analyses.
Bleaching was corrected by fitting appropriate negative exponential curves to each response curve [ 72].
Mid -p exact confidence intervals were derived, and all hypothesis tests (for example, of heterogeneity of OR by heritability subgroup and age) were based on fitting appropriate generalisations of the above logistic model, with interaction terms to test for the desired effect (for example, departure from homogeneity) (Cox and Hinkley, 1974), and reported in Table 5.
The results of the EIS studies were analyzed by fitting the appropriate equivalent circuit.
All trials were separately analyzed by fitting an appropriate spatial model with rows and columns using PBTools (bbi.irri.org).org
Effect modification by sex was explored by fitting interaction terms into the full model.
Effect modification by sex was examined in stratified analyses as well as by fitting interaction terms.
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