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To do this we applied the Peaks over Threshold (POT) method, by fitting a Generalized Pareto distribution (GPD) to all the skew surges that exceeded the 99.75th percentile, at each site in turn.
IDF relationships were derived by fitting a generalized extreme value distribution to the annual maximum series for durations of 20 min, 1 h and 4 h.
To identify genes with significant expression profile differences over time between retinal developmental stages, we used Next-maSigPro19, an R Bioconductor package that works by fitting a generalized linear model with negative binomial dispersion to the library-corrected gene reads counts, but explicitly accounting for the time-dependence of the polynomial model.
Factors influencing the maximum gametocyte density of either P. falciparum or P. vivax were analysed by fitting a Generalized Linear Model (GLM) with a Poisson error structure (loglinear regression).
Factors influencing the maximum parasite density of either P. falciparum or P. vivax were analysed by fitting a Generalized Linear Model (GLM) with a Poisson error structure (loglinear regression).
We begin by fitting a generalized additive model (GAM) [ 55] to the numerical abundance time series of each core species.
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We have studied the potential of detecting variance-controlling QTL by fitting a double generalized linear model via a two-stage procedure to simulated phenotype and marker information.
Designs for fitting a generalized linear model depend on the unknown parameters of the model.
Differential expression was evaluated by fitting a negative binomial generalized linear model for each feature and then adjusting the P-value for multiple testing using the Benjamini-Hochberg correction [ 78] with a false discovery rate (FDR) of 0.05.
Differential enrichment was then tested by fitting a multi-factor generalized linear model (GLM) using EdgeR [ 67]; each of the experimental pair-wise comparisons was denoted as a separate contrast (see EdgeR tutorial).
The functional form of the exposures and each continuous covariate was explored by fitting a smooth function in a generalized additive model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com