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Differentiation of effector and memory CD8+ T cells is accompanied by extensive changes in the transcriptome and histone modifications at gene promoters; however, the enhancer repertoire and associated gene regulatory networks are poorly defined.
Germination of cereals was accompanied by extensive changes in the redox state of seed proteins.
Cell transformation by the Src tyrosine kinase is characterized by extensive changes in gene expression.
Furthermore, the transition from healthy to disease tissue is accompanied by extensive changes in miRNA profiles.
Nonetheless, AMsh glia remodeling requires membrane growth and is therefore likely mediated by extensive changes in the glial cytoskeleton.
In microarray experiments, we and others found rd1 degeneration to be accompanied by extensive changes in gene expression.
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Ms. White's approach could well signal more vigorous enforcement by the S.E.C. against companies found to have violated the law by requiring extensive changes in their operations in addition to the usual financial penalties.
The Sant'Egidio Community is one of a number of new lay movements that have emerged to fill gaps opened by the extensive changes in Roman Catholicism's devotional and organizational life after the Second Vatican Council.
More generally, chromosomal instability could provide a growth advantage to the cancer cell by causing extensive changes in gene expression via increased cell proliferation or decreased cell death.
The many loci differentially regulated by MT19c suggest extensive changes in epigenetic control by MT19c.
Human activities are also responsible for high levels of pollution by synthetic chemicals, extensive changes in landscape structure and the release of many species from dispersal limitation.
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Justyna Jupowicz-Kozak
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