Sentence examples for by extensive cell death from inspiring English sources
Knockdown of ttk resulted in normal oogenesis until approximately stage 6, followed by extensive cell death.
One of the major genetic dysfunctions initiating cancer is telomere crisis, which is characterized by extensive cell death and concomitant cytogenetic abnormalities [ 18].
131 Short-term dynamics in productively infected CD4+ T cells are characterized by a rapid exponential increase of virus replication followed by extensive cell death.
It suggests that the gross developmental abnormalities observed in hif2α morphants is possibly caused by extensive cell death occurred in the early stage of development.
The control Eμ-myc/MSCV lymphomas invariably exhibited a high proliferation index accompanied by extensive cell death, as evidenced by the widespread 'starry sky' pathology and cleaved caspase 3 staining.
Disappearance of STAT-GFPdestab was not caused by cells switching off the JAK-STAT pathway but rather by extensive cell death (Fig. 2B, compare with the uninfected control in 2C), something that would correlate with the observed loss of epithelial tissue.
Expression of Wg, Dsh, or Arm driven by GMR-Gal4 promotes extensive cell death as revealed by AO staining and TUNEL assay that visualizes dying cells, and produces eyes with reduced size.
As repression of SIK3 alone resulted in a mild extension of mitosis (Supplementary Figure S2A) rather than the extensive cell death induced by inhibition of classic mitotic kinases such as PLK1, SIK3 probably may not be a very effective stand-alone target.
RNA and DNA were isolated as outlined below, however, if there were less than 104 cells after treatment due to extensive cell death by 5-AZA treatment, the cells were lysed with 0.3% Nonidet P40, 20 U RNAsin, 0.01 M DTT [30] and the supernatant was placed in TriPure for RNA extraction while the cell nuclei were bisulfite modified.
Furthermore, expression of APP in the developing wing pouch driven by sd-Gal4 (sd>APP) provoked extensive cell death and generated a small wing phenotype in the adults (Supplementary Figure S2b).
Interestingly, retina damage caused by different concentrations of ouabain generates extensive cell death of retina neurons and promotes the surviving Müller glia to proliferate robustly within a 3- to 12-day period [ 54].
